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. 2013 Jul 10;13:166. doi: 10.1186/1472-6882-13-166

Figure 8.

Figure 8

Caspase activities in CACF-treated cells. (A) Caspase-3/7, -8 and -9 activities in the CACF (12.5 μg/mL)-treated A375 cells were measured in luminescence against various time intervals. Activity of caspase-9 was increased followed by caspase-3/7 activities after CACF treatment. (B) A375 cells were pretreated with inhibitors for pan-caspase (Z-VAD-FMK), caspase-3 (Z-DEVD-FMK), caspase-9 (Z-LEHD-FMK) or caspase-8 (Z-IETD-FMK) before adding CACF. Caspase-3/7 activities in CACF-treated cells were then determined by luminescence assays. Data were mean ± SD of fluorescence intensity readings measured from different photos taken (*P<0.05).