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. Author manuscript; available in PMC: 2014 Jun 28.
Published in final edited form as: J Nat Prod. 2013 Jun 3;76(6):1175–1181. doi: 10.1021/np400320r

Figure 3.

Figure 3

Concentration-response results of 1–9 in a T47D cell-based reporter assay for HIF-1 activity. The compound 1,10-phenanthroline (1,10-phen) was used as a positive control. T47D cells transfected with the pHRE-luc construct were exposed to compounds at the specified concentrations for 16 h. Luciferase activity was normalized to that of the untreated control and presented as “Relative Luciferase Activity.” Data shown are average + standard deviation (n = 4). An asterisk (*) indicates p < 0.05 when compared to the untreated control.