Table 2. Effect of leptin on the FGR ratio, birth weight, and placental weight of neonatal rats.
Group | Number of neonates | Birth Weight (g) | Placental Weight (g) | FGR Ratio (%) |
Sham control | 72 | 5.91±0.52* | 0.76±0.19# | 2.77±0.65* |
FGR+PBS | 57 | 4.70±0.71 | 0.55±0.04 | 60.78±12.5 |
FGR+leptin | 50 | 5.09±0.45# | 0.56±0.09 | 27.14±4.4* |
The number of neonates was recorded, and the weights of the placenta and the birth weight of the baby were measured within 24 hour after delivery. Newborn pups were considered with growth restriction when the iBW was below -2 SD of the mean iBW of the pups in the control group. The FGR ratio was determined by the number of FGR pups in relation to the total number of pups. Data are presented as mean ± SD.
P<0.05,
P<0.01 vs PBS-treated FGR group (n = 10).