Table 3.

Treatment regimens of study patients

Treatment regimen	All patients	Patients with delayed haemolysis,
	n = 36	n = 5/16*
Quinine (iv) + Clindamycin (po)	9	0/4
Quinine (iv) + Doxycycline (po)	16	0/3
Quinine (iv) monotherapy	1	0/1
Quinine (iv) + Clindamycin (po) + Artesunate (ir)	1	1/1
Quinine (iv) + Doxycycline (po) + Artesunate (ir)	3	1/2
Quinine (iv) + Artesunate (ir)	1	0/1
Artesunate (iv) with subsequent Atovaquone/Proguanil (po)	4	2/3
Artesunate (iv) with subsequent Mefloquine (po)	1	1/1

*a total of n = 16 contributed data for the primary endpoint assessment (delayed haemolysis).

Abbreviation: iv intravenous, po orally, ir intrarectal.