Table 4.

Demographic and clinical parameters of patients with post-treatment haemolysis

Patient	Gender	Travel type	Country of infection	Anti-malarial treatment	Baseline parasitaemia	Other complications	Pre-existing medical conditions	Coombs test	Transfusions for post-treatment haemolysis
1	f	Tourism	Burkina Faso	Quinine (iv) + Clindamycin (po) + Artesunate (ir)	30%	Acute renal failure (Peak creatinine: 8.5 mg/dl), QTc prolongation (550 ms)	Hypertension	DCT negative	Day 15 and Day 21 (2 units of packed red blood cells each)
2	m	VFR	Burkina Faso	Quinine (iv) + Doxycycline (po) + Artesunate (ir)	25%	Acute renal failure (Peak creatinine: 2.2 mg/dl)	Newly diagnosed HIV-1 infection	DCT positive, warm auto-antibodies (IgG)	Day 14 (2 units of packed red blood cells)
3*	f	Tourism	Uganda	Artesunate (iv) + Mefloquine (po)	14%	-	-	DCT not done	None
4*	m	Tourism	Gambia	Artesunate (iv) + Atovaquone/ Proguanil (po)	21%	Acute renal failure (peak creatinine: 6.5 mg/dl)	Hypertension	DCT positive, Low titre of anti-E IgG antibodies	Day 14 and Day 21, 2 units of packed red blood cells
5*	m	Tourism	Gambia/ Senegal	Artesunate (iv) + Atovaquone/ Proguanil (po)	20%	Acute renal failure (peak creatinine: 7.0 mg/dl)	-	DCT negative	None

*patients have been previously described in detail [15].

Abbreviation: iv intravenous, po orally, ir intrarectal.