Table 1.
Study 1: Genome detection in ferrets challenged at day 20 post vaccination
| Ferret# - dose HeVsG | Ab titre to NiV at challenge | Eut dpc |
Genome detected by PCR (dpc) |
Virus positive tissues | |||||
|---|---|---|---|---|---|---|---|---|---|
| Oral swab | Rectal swab | Blood | Nasal wash | Urine | Tissues | ||||
|
1-0 |
<2 |
6 |
PM |
PM |
PM |
PM |
PM |
13/13 |
8/13 |
|
2-0 |
<2 |
10 |
6, 8, PM |
8, PM |
8, PM |
8, PM |
PM |
13/13 |
6/13 |
|
3-4 |
64, 64 |
21 |
- |
- |
- |
- |
- |
0/13 |
ND |
|
4-4 |
NC |
na |
NC |
NC |
NC |
NC |
NC |
NC |
ND |
|
5-20 |
256, 256 |
21 |
- |
- |
- |
- |
- |
0/13 |
ND |
|
6-20 |
256, 512 |
21 |
- |
- |
- |
- |
- |
0/13 |
ND |
|
7-100 |
NC |
na |
NC |
NC |
NC |
NC |
NC |
NC |
ND |
| 8-100 | 256, 512 | 21 | - | - | - | - | - | 0/13 | ND |
Ab antibody, Eut dpc day post challenge that ferrets were euthanized PM post mortem, NC no challenge, ND not done; -, no viral RNA detected, na not applicable.