Table 4. Susceptibility test towards different antibiotics of A. xylosoxidans NH44784-1996 and 10 clinical isolates taken from the same patient in the years from 1996 to 2011 and three A. xylosoxidans reference strains DMS2402, DSM6388 and DSM11852.
Clinical isolates collected at consecutive years from 1996
|
Reference strains
|
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Antibiotic | 0 | 2 | 7 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | DSM 2402 | DSM 6388 | DSM 11852 |
Tobramycin | 96 | 32 | 96 | 128 | 128 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 12 | 1 |
Meropenem | 0.25 | 6 (32) | 32 | 32 | 12 (32) | 32 | 32 | 8 (32) | 32 | 16 (32) | 12 (32) | 0.5 | 0.125 | 0.016 |
Ceftazidime | 4 | 4 | 16 | 8 | 16 | 12 | 12 | 8 | 8 | 6 | 8 | 8 | 3 | 0.38 |
Aztreonam | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 192 | 12/256 |
Piperacillin | 1 | 1.5(12) | 3 | 2 | 1.5 | 0.75(3) | 2 | 1.5 | 1.5 | 1.5 | 1.5 | 1 | 1 | 0.125 |
P+T | 0.5 | 0.75(6) | 1.5 | 1.5 | 0.75 | 0.5 (1.5) | 2 | 1 | 0.75 | 0.75 | 0.75 | 0.5 | 0.5 | 0.064 |
Colistin | 12 | 2 | 12 | 2 | 4 | 16 | 3 | 2 | 3 | 3 | 4 | 12 | 12 | 0.5 |
Ciprofloxacin | 6 | 16 | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 1.5 | 0.25 |
T+S | 0.47 | 0.19(12) | 3/(32) | 10 (32) | 3/(32) | 3/32 | 2/(32) | 1 (32) | 0.38(32) | 1 (32) | 32 | n.t. | n.t. | n.t. |
Tetracycline | 64 | 96 | 256 | 128 | 256 | 256 | 96 | 256 | 256 | 256 | 256 | n.t. | n.t. | n.t. |
Chloramphenicol | 64 (256) | 256 | 256 | 96 | 256 | 128 (256) | 256 | 128 (256) | 256 | 256 | 192 | n.t. | n.t. | n.t. |
P+T: Piperacillin+Tazobactam, T+S: Trimethoprim+Sulfamethoxacole. Numbers in brackets relate to subpopulations. n.t.: not tested.