Figure 2. Cardiac expression of vWf at 6 months after irradiation.

In sham-irradiated hearts, vWF immunoreactivity was only found on the endothelium of larger arteries, while in irradiated hearts vWF was also found in endothelial cells of capillaries and arterioles, and in some hearts in the extracellular matrix (A). Areas immunoreactive for vWf were not altered by PTX or TSB (B). Average ± SEM, n=8-9. *Significant difference with sham-irradiation (p<0.05). Scale bar: 100 μm.