Table 1. Left ventricular mRNA levels of TM, Nrg-1, and PKCα at 6.
Experimental group | TM | Nrg-1 | PKCα |
---|---|---|---|
Sham | 1.04 ± 0.14 | 1.58 ± 0.69 | 1.01 ± 0.08 |
21 Gy | 1.38 ± 0.11 | 3.79 ± 0.50* | 2.13 ± 0.13* |
21 Gy + PTX | 1.84 ± 0.20† | 3.50 ± 0.40 | 1.70 ± 0.20* |
21 Gy + PTX/TSB | 1.76 ± 0.23† | 5.61 ± 0.48*† | 1.78 ± 0.09* |
Relative mRNA levels were measured with real-time PCR at 6 months after local heart irradiation (average ± SEM, n 5).
* Significant difference with sham-irradiation (p<0.05), † Significant difference with 21 Gy (p<0.05).