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. 2013 Jul 22;8(7):e68762. doi: 10.1371/journal.pone.0068762

Table 1. Left ventricular mRNA levels of TM, Nrg-1, and PKCα at 6.

months.

Experimental group TM Nrg-1 PKCα
Sham 1.04 ± 0.14 1.58 ± 0.69 1.01 ± 0.08
21 Gy 1.38 ± 0.11 3.79 ± 0.50* 2.13 ± 0.13*
21 Gy + PTX 1.84 ± 0.20 3.50 ± 0.40 1.70 ± 0.20*
21 Gy + PTX/TSB 1.76 ± 0.23 5.61 ± 0.48* 1.78 ± 0.09*

Relative mRNA levels were measured with real-time PCR at 6 months after local heart irradiation (average ± SEM, n 5).

* Significant difference with sham-irradiation (p<0.05), † Significant difference with 21 Gy (p<0.05).