Table A3.
Associations Between 1992 Prediagnostic Processed Meat Intake and Mortality Among 2,315 Patients With CRC (1,282 men and 1,033 women) in the Cancer Prevention Study II Nutrition Cohort
| Outcome | Quartile of Prediagnostic Processed Meat Intake (servings/week)* |
Ptrend‡ | Continuous Meat Intake (servings/week) |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q1† |
Q2 |
Q3 |
Q4 |
||||||||||||||||
| Total Deaths | Person-Years | RR | 95% CI | Total Deaths | Person-Years | RR | 95% CI | Total Deaths | Person-Years | RR | 95% CI | Total Deaths | Person-Years | RR | 95% CI | RR | 95% CI | ||
| All-cause mortality | 199 | 3,802 | 265 | 4,931 | 237 | 4,545 | 265 | 4,187 | |||||||||||
| Base model§ | 1.00 | — | 1.13 | 0.94 to 1.37 | 1.03 | 0.85 to 1.25 | 1.25 | 1.04 to 1.52 | .04 | 1.02 | 1.00 to 1.05 | ||||||||
| Multivariable model 1‖ | 1.00 | — | 1.15 | 0.95 to 1.39 | 1.02 | 0.83 to 1.24 | 1.21 | 0.99 to 1.48 | .14 | 1.02 | 0.99 to 1.04 | ||||||||
| CRC mortality | 86 | 3,802 | 122 | 4,931 | 98 | 4,545 | 107 | 4,187 | |||||||||||
| Base model§ | 1.00 | — | 1.17 | 0.88 to 1.55 | 0.97 | 0.73 to 1.31 | 1.10 | 0.83 to 1.47 | .97 | 0.99 | 0.95 to 1.03 | ||||||||
| Multivariable model‖ | 1.00 | — | 1.20 | 0.90 to 1.60 | 0.98 | 0.72 to 1.33 | 1.09 | 0.80 to 1.48 | .92 | 0.98 | 0.94 to 1.03 | ||||||||
| Cardiovascular disease mortality | 38 | 3,802 | 43 | 4,931 | 45 | 4,545 | 50 | 4,187 | |||||||||||
| Base model§ | 1.00 | — | 1.08 | 0.68 to 1.70 | 1.09 | 0.69 to 1.71 | 1.48 | 0.95 to 2.30 | .04 | 1.06 | 1.01 to 1.11 | ||||||||
| Multivariable model‖ | 1.00 | — | 1.08 | 0.68 to 1.71 | 1.07 | 0.67 to 1.70 | 1.47 | 0.92 to 2.33 | .06 | 1.07 | 1.01 to 1.12 | ||||||||
| All other causes of mortality | 75 | 3,802 | 100 | 4,931 | 94 | 4,545 | 108 | 4,187 | |||||||||||
| Base model§ | 1.00 | — | 1.12 | 0.82 to 1.52 | 1.07 | 0.78 to 1.46 | 1.35 | 0.99 to 1.82 | .06 | 1.04 | 1.00 to 1.07 | ||||||||
| Multivariable model‖ | 1.00 | — | 1.10 | 0.81 to 1.50 | 1.02 | 0.74 to 1.40 | 1.27 | 0.92 to 1.75 | .17 | 1.03 | 0.99 to 1.07 | ||||||||
Abbreviations: CRC, colorectal cancer; Q, quartile; RR, relative risk.
Quartiles in men: < 1.04, 1.04- < 2.23, 2.23- < 4.16, ≥ 4.16; quartiles in women: < 0.23, 0.23- < 1.04, 1.04- < 2.22, ≥ 2.22.
Reference quartile.
Ptrend calculated by using the median meat intake in each quartile, specific to sex.
Base model adjusted for age at diagnosis and sex.
Multivariable model adjusted for age at diagnosis, sex, tumor stage at diagnosis, 1992 prediagnostic energy intake (sex-specific quartiles), 1992 body mass index, history of diabetes, and history of myocardial infarction.