Table 5.

Adverse Events

Complication	Control (n = 44)	ILD-rFVIIa (n = 44)	p Value
Reoperation for bleeding	1 (2.3%)	0	0.31
Delayed sternal closure	2 (4.5%)	2 (4.5%)	1
Deep sternal wound infection	0	0	1
New-onset arrhythmia	15 (34.1%)	19 (43.2%)	0.51
Pacemaker placement	3 (6.8%)	2 (4.5%)	0.65
Peak postoperative creatinine (mg/dL)	1.4 (1.2–1.7)	1.4 (1.1–2.0)	0.80
Acute renal failure (Cr > 2.0 and > 2× baseline)	3 (6.8%)	5 (11.4%)	0.46
New-onset dialysis	1 (2.3%)	1 (2.3%)	1
Prolonged ventilation (> 24 hours)	11 (25%)	7 (15.9%)	0.43
Tracheostomy	4 (9.1%)	0	0.12
Myocardial infarction	0	1 (2.3%)	0.31
Pulmonary embolism	1 (2.3%)	1 (2.3%)	1
Mesenteric ischemia	1 (2.3%)	0	0.31
Any stroke (neurologic deficit lasting > 72 hours)	3 (6.8%)	1 (2.3%)	0.62
Embolic stroke	2 (4.5%)	0	0.49
Permanent paraparesis/paraplegia	1 (2.3%)	0	0.31
Postoperative length of stay (days)	6 (5–9)	7 (5–11)	0.33
30-day/in-hospital death	1 (2.3%)	1 (2.3%)	1

Values expressed as median (interquartile range) or number (percent).

Cr = creatinine; ILD-rFVIIa = intraoperative low-dose recombinant activated factor VII.