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Multienzyme complex for the anaerobic production of PUFAs in deep-sea bacteria. The PKS multienzyme for the anaerobic production of eicosapentaenoic acid (EPA) in Photobacterium profundum contains five required genes (Pfa A,B,C,D, and E). The DH domains identified by sequence homology to FabA/Z are arranged in tandem and housed within the PfaC multienzyme. This arrangement of domains is well conserved among deep-sea bacteria that produce PUFAs.
