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A) Single adenocarcinoma cells show convoluted nuclei and cytoplasmic vacuolization (arrows). A few neutrophils are seen in the tumour stroma (case 3). Semithin section; Giemsa x400; B) single adenocarcinoma cell characterized by marked chromatin condensation, convoluted nucleus, loss of microvilli and mitochondrial swelling (arrow). The adjacent tumor cells appear morphologically well preserved (case 4), x6000.
