Fig. 2.

Morphological changes of normal human melanocytes HEMa- LP exposed to different amikacin concentrations for 24 h.

Cell monolayer treated with the lowest concentration of amikacin (b - 0.075 mmol/l) is similar to the control culture (a - free of antibiotic). The higher concentrations of amikacin induced detectable changes in cell morphology (c - 0.75 mmol/l, d - 7.5 mmol/l). Cells were observed under an inverted microscope at ×200 magnification.