Table 1.
Baseline Characteristics of Men with Incident MI and Matched Controls During 10 Years of Follow-up‡
Characteristics | Cases (n = 454) |
Controls (n = 900) |
P Value |
||
---|---|---|---|---|---|
Age, mean (SD), y | 63.8 | (8.6) | 63.8 | (8.6) | |
Current smoker | 42 | (9.3) | 80 | (8.9) | |
Body mass index, mean (SD)† | 26.1 | (3.3) | 25.6 | (3.4) | 0.01 |
Major ancestry | |||||
White | 427 | (94.1) | 851 | (94.6) | 0.70 |
African American | 0 | 2 | (0.22) | 0.55 | |
Asian | 3 | (0.7) | 5 | (0.6) | 1.0 |
Other | 24 | (5.3) | 42 | 4.7) | 0.62 |
Region of residence | |||||
South | 197 | (43.5) | 426 | (47.3) | 0.17 |
Northeast | 146 | (32.2) | 313 | (34.8) | 0.34 |
Midwest | 111 | (24.4) | 161 | (17.9) | 0.004 |
Family history of MI before age 60 y | 72 | (15.9) | 100 | (11.1) | 0.01 |
Current aspirin use, ≥2/wk | 177 | (39.0) | 310 | (34.4) | 0.10 |
History of diabetes | 42 | (9.3) | 33 | (3.7) | <0.0001 |
History of hypertension | 169 | (37.2) | 265 | (29.4) | 0.004 |
Fat intake, mean (SD), % energy | |||||
Total | 30.6 | (6.7) | 30.2 | (6.9) | 0.40 |
Saturated fat | 10.2 | (2.7) | 10.0 | (2.9) | 0.22 |
Marine omega-3 | 0.12 | (0.16) | 0.13 | (0.20) | 0.85 |
Alcohol consumption, median (IQR), g/d | 4.2 | (0–14.6) | 6.9 | (0.88–17.8) | 0.002 |
Multivitamin use | 211 | (46.5) | 436 | (48.44) | 0.49 |
Physical activity, median (IQR), MET-h/wk | 22.8 | (9.5–46.5) | 26.1 | (11.9–48.8) | 0.05 |
Cholesterol level, mean (SD), mg/dL | |||||
Total | 210.7 | (39.0) | 202.4 | (36.3) | 0.0001 |
HDL | 42.2 | (11.1) | 46.0 | (12.6) | <0.0001 |
LDL | 133.9 | (34.5) | 126.0 | (31.2) | <0.0001 |
Triglycerides level, mean (SD), mg/dL | 164.4 | (100.4) | 142.6 | (101.4) | 0.0002 |
25(OH)vitamin D, mean (SD), ng/mL | 23.0 | (7.6) | 24.5 | (8.3) | 0.002 |
Abbreviations: HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; MET-h, metabolic equivalent task-hours; MI, myocardial infarction.
SI conversions: To convert total, HDL, and LDL cholesterol to mmol/L, multiply by 0.0259. To convert triglycerides to mmpl/L, multiply by 0.0113.
Data are expressed as No. (%) unless otherwise indicated. Age, smoking status, and month of blood draw were matched variables.
Body mass index is expressed as weight in kilograms divided by the square of height in meters.