FIG. 5.

Macroscopic and microscopic photomicrograph of the rat's colon: (a, A) normal colon tissue from the control group, (b, B) are representing, respectively, the macroscopic ulcerative and hemorrhagic epithelium with edematous and severe infiltration of inflammatory cells in lamina propria of distal colon from untreated colitis-positive animals, (c, C) are showing the macroscopic and microscopic features of the mesalamine-treated rats with remarkable improvement, (d, D) are demonstrating the macroscopic and microscopic appearance of distal colon from the atorvastatin-treated animals, (e, E) are illustrating the macroscopic and microscopic feature of the distal colon from the hawthorn berry extract (HBE)-received animals with an approximately normal epithelium and a submucosal structure, (f, F) are showing the macroscopic and microscopic architecture of the distal colon from the HBE and mesalamine-treated group with a relatively improved structure, and (g, G) are illustrating the macroscopic and microscopic features of the distal colon from HBE and atorvastatin-received rats. Eosin and hematoxylin staining; magnification: (A, B) 100×, (C–G) 400×.