Coculture of S. mutans with L. lactis or Staphylococcus warneri. The methods for the coculture assay are described in the supplemental material. Populations of S. mutans were determined after L. lactis (A) or S. warneri (B) cells were cocultured with UA159, nsrRS mutant, or lcrRS mutant cells. *, P < 0.01, as determined using Dunnett's method, for the percentage of the S. mutans population.