Table 1.
Susceptibilities of TCS deletion mutants to various bacteriocins
| Strain | Susceptibilitya to: |
||||||
|---|---|---|---|---|---|---|---|
| Class I |
Class IIa, munditicin | Class IIb, mutacin IV | Class IIc, lactocyclicin Q | Class IId, lacticin Q | |||
| Nisin A | Nukacin ISK-I | Lacticin 481 | |||||
| UA159 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS45 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS1 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS2 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS3 | 8 (4) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS4 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS5 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS6 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS7 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS8 | 1 (64) | 8 (8) | 7 | 5 | 0 | 3 | 8 |
| TCS9 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS10 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS11 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS12 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS13 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
| TCS14 | 1 (64) | 1 (64) | 1 | 5 | 0 | 3 | 8 |
a
Susceptibility was based on direct analysis (the diameter of inhibition [in mm]), with the exception of the two class I drugs on which this study was focused, nisin and nukacin ISK-I, for which MICs were also determined (MIC values [in μg/ml] are shown in parentheses).