Table 1.
Binding of C. jejuni strain 81-176 and H. pylori strain 26695 to natural mucins on a mucin microarray
Mucin sourcea | Level of bindingb of: |
|
---|---|---|
C. jejuni 81-176 | H. pylori 26695 | |
Abomasum (B) | 2,780 | 2,158 |
Cervicovaginal (B) | 472 | 521 |
Cervix (B) | 497 | 505 |
Duodenum (B) | 795 | 289 |
Spiral colon (B) | 1,131 | 288 |
Trachea (B) | 533 | 261 |
Endometrium (B) | 554 | 177 |
Cecum (C) | 3,884 | 387 |
Proximal small intestine (C) | 8,775 | 625 |
Large intestine (C) | 14,344 | 571 |
Abomasum (D) | 2,021 | 2,261 |
Duodenum (D) | 121 | 487 |
Jejunum (D) | 144 | 653 |
Spiral ascending colon (D) | 816 | 172 |
HT29-MTX-E12 cells | 3,192 | 1,108 |
Dorsal ascending colon (E) | 925 | 2,036 |
Duodenum (E) | 1,183 | 1,794 |
Left ventral ascending colon (E) | 1,883 | 965 |
Right ventral ascending colon (E) | 3,255 | 1,786 |
Jejunum (E) | 1,891 | 3,064 |
Stomach (E) | 218 | 493 |
Trachea (E) | 313 | 404 |
LS174T cells | 4,298 | 14,409 |
Cecum (M) | 483 | 1,157 |
Large intestine (M) | 1,001 | 1,907 |
Small Intestine (M) | 202 | 353 |
Stomach (M) | 694 | 1,074 |
Abomasum antrum (O) | 343 | 1,126 |
Descending colon (O) | 866 | 1,826 |
Duodenum (O) | 1,576 | 1,124 |
Ileum (O) | 724 | 778 |
Jejunum (O) | 652 | 1,393 |
Spiral colon (O) | 2,654 | 7,759 |
Cecum (P) | 4,221 | 6,038 |
Descending colon (P) | 1,423 | 256 |
Jejunum (P) | 1,055 | 2,903 |
Spiral colon (P) | 1,211 | 3,372 |
Stomach (P) | 2,522 | 7,915 |
Cecum (R) | 1,031 | 4,302 |
Colon (R) | 1,011 | 482 |
Duodenum (R) | 902 | 5,827 |
Ileum (R) | 501 | 1,446 |
Stomach (R) | 1,101 | 4,688 |
B, bovine; C, chicken; D, deer; E, equine; M, mouse; O, ovine; P, porcine; R, rat.
Expressed as the mean fluorescence intensity (in relative fluorescence units) from duplicate individual microarrays across 3 different array slides. The binding temperature was 37°C.