Fig 2.
In vivo pathogenicity of M28, M5-90, and mutant strains in BALB/c mice. Different groups of animals were inoculated (i.p.) with 105 CFU of each strain, and spleens were collected at different times p.i. (A) Viable spleen homogenate titers (CFU) as determined by triplicate serial dilution and plating. (B) Mouse spleen weights at different times p.i. All data points are means (n = 5); error bars are standard deviations. Any groups that are not significantly different from one another will have the same lowercase letter on the right of each panel. Different letters indicates significant differences by Student's t test (P < 0.01).