Table 2.

Single-nucleotide polymorphisms (SNPs) between B. melitensis vaccine strain M5-90 and virulent strains M28, 16 M, and ATCC 23457

Virulent strain	No. of SNP differences in virulent strains versus M5-90								M5-90 base
	Chromosome I				Chromosome II
	A	C	G	T	A	C	G	T
M28
		6	17	4		0	0	0	A
	8		9	8	0		1	0	C
	14	16		11	2	3		0	G
	4	11	7		1	0	3		T
ATCC 23457
		17	50	8		4	17	1	A
	14		13	26	2		6	12	C
	44	20		18	19		4	4	G
	6	43	11		6	22	4		T
16 M
		87	307	46		42	181	18	A
	90		101	338	51		59	173	C
	339	86		94	178	52		48	G
	37	307	108		27	147	43		T