Table 3.

Genotypes and phenotypes of mutants for cationic antibacterial compounds^a

Parent and mutant strain	Selective agent	norA mutation	MIC (mg/liter)						MBC (mg/liter)
			NOR	CIP	EB	AF	CHX	BZC	NOR	CIP	EB	AF	CHX	BZC
ATCC 25923		Wild type	1	1	16	32	2	2	8	1	16	64	2	4
MO060	AF	A94T	16	8	64	256	4	4	16	8	128	256	8	8
MO061	AF	T91A	8	4	32	256	4	4	8	4	64	256	4	4
MO062	AF	T126A	8	4	128	256	4	4	16	4	128	256	32	8
MO072	EB	T126A	8	4	128	256	4	4	8	4	128	256	4	4
MO058	EB	T126A	8	2	128	256	4	4	8	16	128	256	32	16
MO059	EB	T126A	8	4	128	256	4	4	8	4	128	256	4	4
ATCC 6538		Wild type	1	0.5	4	16	4	2	2	0.5	16	32	4	8
MO063	AF	A107G	8	4	32	128	4	4	8	4	32	256	4	4
MO064	AF	T126A	8	2	32	128	4	4	8	4	64	256	4	8
MO065	AF	T126A	8	2	32	128	4	4	8	4	64	256	8	4
MO037	CHX	T89G	16	4	32	64	8	4	16	4	64	128	128	4
MO038	CHX	T89G	16	4	256	256	4	4	16	4	256	256	8	8
MO039	CHX	T90G	8	4	256	256	4	4	8	4	256	256	16	8
MO040	CHX	T90G	8	4	32	64	4	4	16	4	128	64	32	4
MO041	CHX	T90G	8	4	16	256	4	4	8	4	64	256	64	4
RN4220		Wild type	1	0.5	8	16	8	2	2	1	16	32	8	2
MO069	AF	A107G	8	4	64	256	4	4	8	4	128	256	8	8
MO070	AF	A107G	16	8	64	256	4	4	16	8	128	256	8	8
MO071	AF	T126A	8	4	64	128	4	8	16	4	64	256	4	8
MO066	EB	T126A	16	4	128	256	4	4	16	8	128	256	8	8
MO067	EB	A107G	8	4	64	256	4	4	16	4	128	256	8	8
MO068	EB	T126A	16	4	64	256	4	4	16	8	128	256	32	8
MO042	CHX	A130C T126A	8	4	256	256	8	4	16	8	256	256	8	4
MO043	CHX	A130C T126A	16	4	256	256	8	4	16	8	256	256	32	4
MO044	BZC	A130C T126A	16	4	128	256	4	8	16	16	256	256	8	8
MO045	BZC	A130C T126A	16	8	128	256	8	4	16	8	128	256	8	8

^aNOR, norfloxacin; CIP, ciprofloxacin; EB, ethidium bromide; AF, acriflavine; CHX, chlorhexidine; BZC, benzalkonium chloride.