Table 1.

Phenotypic and genotypic characteristics of OXA-48-producing isolates obtained from patients 1 and 2 and of transformants, transconjugants, and corresponding recipient strains used in this study

Strain	Presence of blaOXA-48-carrying plasmid		MIC (μg/ml)				Modified Hodge test result
	60 kb	160 kb	Imipenem	Ertapenem	Meropenem	Doripenem
Clinical isolates
K. pneumoniae KPa	+	−	0.75	3	0.38	0.5	+
K. pneumoniae KP1a	−	+	0.5	2	0.38	0.38	+
E. coli EC1	+	−	2	3	0.38	0.75	+
E. coli EC1a	−	−	0.19	0.012	0.012	0.016	−
K. pneumoniae KP2a	+	−	0.75	4	0.75	0.75	+
E. cloacae ECL2	+	−	6	3	0.38	0.25	+
K. oxytoca KO2	+	−	0.75	1.5	0.75	0.25	+
Other strains
E. coli DH10B	−	−	0.19	0.012	0.016	0.023	−
E. coli DH10B-T1	+	−	0.75	4	0.38	0.38	+
E. coli DH10B-T2	−	+	0.75	2	0.38	0.25	+
E. cloacae LBN600	−	−	0.25	0.25	0.023	0.032	−
E. cloacae LBN600-T1	−	+	0.25	3	0.25	0.25	+
K. oxytoca LBN548	−	−	0.19	0.023	0.016	0.023	−
K. oxytoca LBN548-T1	−	+	0.38	4	0.38	0.38	+

^aIsolate harboring a bla_{CTX-M-1-group}-carrying plasmid.