Table 2.
Comparison of the groups' histopathological injury and apoptotic indicesa
| Parameter | Mean value ± SD for group |
P value |
||||
|---|---|---|---|---|---|---|
| G1 (control) | G2 (colistin) | G3 (colistin + GSPE) | G1 vs G2 | G1 vs G3 | G2 vs G3 | |
| HE score | 0.00 ± 0.00 | 1.85 ± 0.37 | 0.28 ± 0.48 | <0.001 | NS | <0.001 |
| AI | 8.89 ± 2.66 | 32.58 ± 4.38 | 17.67 ± 2.29 | <0.001 | <0.001 | <0.001 |
a
Data are given as means ± standard deviations, and a P value of <0.05 was regarded as significant. Abbreviations: GSPE, grape seed proanthocyanidin extract; G1, group 1; G2, group 2; G3, group 3; HE, hematoxylin-eosin; AI, apoptotic index.