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MICS of metronidazole for B. fragilis clinical isolates and laboratory constructs
| Strain | MIC or MIC range (μg/ml) | Fold changea |
|---|---|---|
| ATCC 25285 | 0.19–0.25 | |
| 638R/pMCL140 | 0.03 | |
| 638R/pMCL140:610nimE | 0.17 | ∼4 |
| 638R/pMCL140:615nimJ | 0.19 | ∼4 |
| 638R/pMCL140:616nimJ | 0.14 | ∼4 |
| HMW610 | 8–16 | |
| HMW615 | 6–8 | |
| HMW616 | 8–24 |
Fold change between strain carrying empty pMCL140 plasmid and strain carrying plasmid with nim insert.
