Table 2.
a Name of the virus based on the status of the Gag epitope and modification of Nef, respectively: x, epitope mutated to nonrecognized variant; i, amino acids inserted to create epitope; r, amino acid substitution to create epitope; WT, unaltered WT HIV-1 Gag or Nef protein sequence; M20A, methionine-to-alanine substitution at amino acid position 20 of Nef.
b Kinetics of transcription for the parent protein (Late, Gag; Early, Nef).
c HLA-I downregulation (Downreg.) function of Nef variant.