Table 3.
Pairwise amino acid identities between the RdRp, S, and N genes of Ty-BatCoV HKU4, Pi-BatCoV HKU5, and MERS-CoV and those of other betaCoVs
| Coronavirus | Pairwise amino acid identity (%) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ty-BatCoV HKU4_2 |
Pi-BatCoV HKU5_31 |
MERS-CoV |
|||||||
| RdRp | S | N | RdRp | S | N | RdRp | S | N | |
| Betacoronavirus lineage A | |||||||||
| HCoV-OC43 | 68.8 | 33.4 | 33.2 | 68.7 | 31.2 | 34.2 | 68.3 | 32 | 35.3 |
| BCoV | 68.7 | 33.5 | 33.2 | 68.6 | 31.3 | 34.8 | 68.2 | 31.3 | 35.6 |
| PHEV | 68.8 | 33.2 | 32.7 | 68.7 | 31.2 | 33.9 | 68.3 | 32.5 | 35.1 |
| GiCoV | 68.7 | 33.9 | 32.8 | 68.6 | 31.6 | 34.8 | 68.2 | 31.4 | 35.3 |
| RCoV | 68.8 | 32.4 | 33.7 | 68.8 | 31.4 | 34.3 | 68.7 | 32 | 34.8 |
| RbCoV HKU14 | 68 | 33.8 | 33.2 | 68 | 30.9 | 34.9 | 68 | 32.2 | 35.3 |
| AntelopeCoV | 68.7 | 33.7 | 32.8 | 68.6 | 31.2 | 34.8 | 68.2 | 31.4 | 35.3 |
| ECoV | 69.1 | 32.4 | 34.9 | 68.7 | 31.5 | 35.6 | 68.3 | 31.6 | 35.7 |
| MHV | 68.7 | 32.7 | 34.1 | 68.8 | 31.9 | 34.7 | 68.6 | 31.5 | 34.3 |
| HCoV-HKU1 | 67.6 | 32.1 | 32.8 | 68.1 | 30.2 | 33.3 | 67.9 | 31.8 | 32.3 |
| Betacoronavirus lineage B | |||||||||
| SARS-CoV | 71.6 | 33.6 | 45.8 | 71.8 | 33.5 | 43.6 | 71.9 | 31.6 | 46.6 |
| SARSr-Rh-BatCoV HKU3 | 71.7 | 33.6 | 45.2 | 71.7 | 32.8 | 43.9 | 71.8 | 30.6 | 46.2 |
| Betacoronavirus lineage C | |||||||||
| Ty-BatCoV HKU4 | 99.5–100 | 97.3–99.6 | 99.5–100 | 92–92.5 | 67.7–68.1 | 73.5–74 | 89.6–90 | 66.8–67.4 | 71.9–72.3 |
| Pi-BatCoV HKU5 | 92.1–92.4 | 67.5–68.4 | 73.7–75.1 | 99.4–99.7 | 88.3–97 | 97.2–98.6 | 92.1–92.3 | 63.4–64.5 | 69.5–70.5 |
| MERS-CoV | 89.9 | 67.3–67.4 | 71.6–72.1 | 92.1 | 64.3 | 68.8–69.5 | |||
| Betacoronavirus lineage D | |||||||||
| Ro-BatCoV HKU9 | 69.3 | 30.8 | 37.3 | 68.7 | 31 | 36.9 | 68.4 | 30.3 | 37.8 |