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(A) The crystallographic structure of a pentamer of FMDV A1061. The residues at VP1-109 and VP1-110 are highlighted in blue and red, respectively. Note that in A1061 the residues at VP1-109 and VP1-110 are K and A, respectively. Also shown is a closer view of the pore at the five-fold symmetry axis, looking down at the outer surface of the pentamer (B) and from a side-on view (C). The residues at these sites are solvent exposed and line the depression surrounding the pore.
