Table 3.
Titers of infectious copy-derived viruses (A/Turkey/2/2006 capsid) with KK or KQ at VP1 109/110 and either KGD or KGE
| Infectious copy plasmid and virus | VP1 109/110a | RGDb | Titer of virus in cell typec |
|||
|---|---|---|---|---|---|---|
| pBTY | BHK | CHO | CHO-677 | |||
| pO1K-A/VP1-Q110K/KGE | K/K | KGE | ||||
| O1K-A/VP1-Q110K/KGE/BHK2/CHO2 | K/K | KGE | CPE | 1.5 × 106 | 3.0 × 104 | 2.0 × 104 |
| O1K-A/VP1-Q110K/KGD | K/K | KGD | CPE | 3.0 × 106 | 9.0 × 103 | 5.0 × 103 |
| pO1K-A/KGE | K/Q | KGE | ||||
| O1K-A/KGD | K/Q | KGD | CPE | 8.5 × 107 | 0 | 0 |
a
Residues at VP1 109 and 110.
b
Residues at the RGD motif site.
c
0, no CPE; CPE, cytopathic effect seen but virus titer not determined.