Table 1.
Baseline characteristics of 988 participants by tertile of high-sensitivity troponin T.
| Tertile of high-sensitivity troponin T |
||||
|---|---|---|---|---|
| Low | Intermediate | High | P-value | |
| Number in Tertile | 330 | 326 | 328 | |
| Range (pg/mL) | <5 - 7.09 | 7.12 - 13.67 | 13.78 - 540.2 | |
| Demographics | ||||
| Age (y) | 60.6 ± 9.8 | 68.1 ± 9.9 | 71.5 ± 10.3 | <.001 |
| Male Sex | 225 (68.2) | 277 (83.9) | 300 (90.9) | <.001 |
| Caucasian | 188 (57.0) | 200 (60.6) | 205 (62.1) | 0.34 |
| Current smoking | 99 (30.0) | 55 (16.7) | 42 (12.7) | <.001 |
| History | ||||
| Hypertension | 217 (65.8) | 231 (70.0) | 245 (74.2) | 0.05 |
| Myocardial Infarction | 163 (49.4) | 174 (52.7) | 189 (57.3) | 0.14 |
| Heart Failure | 36 (10.9) | 48 (14.5) | 89 (27.0) | <.001 |
| Diabetes | 55 (16.7) | 79 (23.9) | 124 (37.6) | <.001 |
| Revascularization | 168 (50.9) | 205 (62.1) | 202 (61.2) | 0.004 |
| Depressive Symptoms | 67 (20.3) | 59 (17.9) | 64 (19.4) | 0.77 |
| Physical Inactivity | 117 (35.5) | 101 (30.6) | 142 (43.0) | 0.004 |
| Measurements | ||||
| Body Mass Index (kg/m2) | 28.5 ± 5.7 | 28.5 ± 5.2 | 28.3 ± 5.2 | 0.9 |
| Systolic Blood Pressure (mmHg) | 130.6 ± 19.0 | 133.3 ± 21.1 | 135.1 ± 22.7 | 0.02 |
| Diastolic Blood Pressure (mmHg) | 75.9 ± 10.4 | 73.9 ± 11.1 | 74.0 ± 12.4 | 0.04 |
| eGFR (mL/min) | 84.1 ± 17.6 | 71.8 ± 17.0 | 55.8 ± 21.7 | <.001 |
| Total Cholesterol (mg/dL) | 181.5 ± 41.4 | 176.0 ± 40.9 | 175.5 ± 45.9 | 0.15 |
| HDL Cholesterol (mg/dL) | 46.7 ± 14.2 | 45.9 ± 13.6 | 44.4 ± 14.3 | 0.11 |
| Medications | ||||
| Beta-blocker | 181 (54.8) | 189 (57.3) | 194 (58.8) | 0.68 |
| ACE-inhibitor or ARB | 129 (39.1) | 175 (53.0) | 200 (60.6) | <.001 |
| Statin | 200 (60.6) | 225 (68.2) | 205 (62.1) | 0.09 |
| Aspirin | 233 (70.6) | 244 (73.9) | 231 (70.0) | 0.39 |
| Diuretics | 62 (18.8) | 84 (25.5) | 145 (43.9) | <.001 |
| Biomarkers | ||||
| NT-proBNP (pg/mL) | 86 (45, 182) | 174 (87, 358) | 473 (175, 1246) | <.001 |
| C-reactive Protein (mg/L) | 2.0 (0.8, 4.3) | 2.0 (0.8, 4.4) | 2.7 (1.2, 6.3) | 0.02 |
Values expressed as N (%), mean ± SD, or median (interquartile range)
Abbreviations: eGFR: estimated glomerular filtration rate; HDL: high-density lipoprotein; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker; NT-proBNP: amino-terminal portion of the prohormone of brain natriuretic peptide.