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. 2013 Apr 16;57(4):586–593. doi: 10.1093/cid/cit246

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© The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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Figure 1. — Statistical summaries of within-participant mean efavirenz (EFV) trough concentrations (C_min), log₁₀ µg/mL. EFV C_min from 324 participants with at least 1 on-rifampin (RIF; open triangles) and off-RIF (open circles) C_min values. EFV C_min from participants with EFV C_min from multiple timepoints have values summarized as the within-participant mean EFV concentration on-RIF and off-RIF. Heavy horizontal lines indicate medians; light horizontal lines indicate Q1 and Q3. P values are obtained from a Wilcoxon signed-rank test of within-participant differences, on-RIF minus off-RIF EFV C_min (within off-RIF quintile). *Statistically significant difference (P ≤ .05). Abbreviations: C_min, trough concentrations; EFV, efavirenz; RIF, rifampin.