Figure 6.

Inhibition of binding of factor H (fH) to mutant strains with ID 1 (A) or ID 55 (B) by mouse antisera (1:50). Negative control fH binding protein (fHbp) knockout strain with 90 µg/mL fH is denoted by the dark grey filled histogram, a mutant strain expressing fHbp incubated with fH alone (no antiserum) is denoted by the light grey filled histogram, a mutant strain expressing fHbp incubated with fH and anti-fHbp ID 4 antiserum is denoted by a thick green line, anti-fHbp ID 9 antiserum is denoted by a dashed pink line, and anti-fHbp ID 13 antiserum is denoted by a thin purple line.