Table 4.

Univariate analysis of factors associated with recurrence in patients with hepatitis C-associated hepatocellular carcinoma treated with liver resection or transplantation (n = 108)

	n (%)	Recurrence, months, median ± SEM	P-value	5-year recurrence, %
Treatment type
Liver transplant	52	Not reached	< 0.001	30.5
Liver resection	56	27.3 ± 5.0		71.5
AFP level
≤ 10 mg/dl	44	99.6 ± NA	< 0.001	28.2
> 10 mg/dl	64	25.9 ± 5.4		69.1
Pathological tumour size
≤ 3 cm	58	99.6 ± 43.1	0.012	44.0
> 3 cm	49	25.9 ± 10.2		63.2
Vascular invasiona
Present	55	17.7 ± 5.4	< 0.001b	87.5
Absent	52	Not reached		27.8
Tumour grade
Good	32	99.6 ± 13.0	0.005	30.1
Moderate–poor	68	27.3 ± 9.3		76.8
Satellites
Present	19	14.0 ± 2.2	< 0.001	92.0
Absent	88	99.6 ± 32.8		44.4
AJCC TNM staging
I	33	85.1 ± NA	0.016	38.9
II	60	47.6 ± 15.8		55.0
III	13	14.5 ± 5.5		79.8
IV	1	–		–

^aMicroscopic or gross.

^bRetained significance in multivariate analysis.

AFP level, alpha-fetoprotein level; AJCC, American Joint Committee on Cancer; NA, not available; SEM, standard error of the mean; TNM, tumour–node–metastasis.