Figure 4.

Peripheral T cells from primary biliary cirrhosis (PBC) patients are enriched preferentially in CXCR3⁺ cells. Peripheral T lymphocytes from PBC (n = 20) and normal controls (NC, n = 20) were isolated from peripheral blood mononuclear cells (PBMCs) via magnetic separation based on CD3 expression. The presence of CXCR3 was assessed by flow cytometry. (a–c) Representative fluorescence activated cell sorter images from normal controls and patients with PBC pre- and post-ursodeoxycholic acid (UDCA) treatment. (d) Mean ± standard error of the mean of CD3⁺ cells of different groups expressing the CXCR3 receptor.