Table 4.
Gene | SNP | Allele | Paternal transmission | Paternal ORa | Maternal transmission | Maternal ORa | P-valueb |
---|---|---|---|---|---|---|---|
DEFA6 | rs4458901 | C | P=0.005 | 2.5 | P=0.65 | 1.15 | 0.09 |
PGR | rs1042839 | C | P=0.47 | 1.3 | P=0.10 | 1.9 | 0.10 |
PTGIS | rs493694 | G | P=0.18 | 1.8 | P=0.03 | 0.90 | 0.07 |
Abbreviations: PTB, preterm birth; SNP, single-nucleotide polymorphism.
OR is odds ratio of having the associated allele versus the other allele.
Null hypothesis: paternal odds ratio=maternal odds ratio.