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. Author manuscript; available in PMC: 2013 Jul 23.
Published in final edited form as: Annu Rev Biophys. 2012 Feb 23;41:295–319. doi: 10.1146/annurev-biophys-042910-155351

Table 1.

Helicases showing Repetitive translocation/unwinding

origin Repetition observed Repetition mechanism Functional implications
Rep Bacterial ssDNA translocation Blockade-induced 3’ capture Prevention of RecA filament formation
UvrD Bacterial ssDNA translocation Duplex-anchored looping and release Removal of RecA filament
PcrA Bacterial ssDNA translocation Duplex-anchored looping and release Removal of RecA filament
NS3 Viral dsDNA unwinding Holding on to unwound strand Unknown
RIG-I Human dsRNA translocation unknown Viral RNA recognition and signaling
BLM Human dsDNA unwinding Strand switching Unknown