Table 2. Statistically significant health parameter changes in the lifestyle intervention group compared with controls after 2 years: results of a randomized controlled trial of the effect of lifestyle changes on erectile dysfunctiona.
| Health parameter | Baseline values of lifestyle intervention group only (mean) | After 2-year lifestyle intervention group only values (mean) | Corrected difference in mean change for lifestyle vs. control group at the end of the 2-year trial |
|---|---|---|---|
| BMI | 36.9 | 31.2 | −5 |
| WHR | 1.02 | 0.93 | −0.08 |
| Weight (kg) | 103 | 88 | −13 |
| Total cholesterol (mmol l−1) | 5.51 | 5.22 | −0.34 |
| HDL cholesterol (mmol l−1) | 1.01 | 1.24 | +0.23 |
| Triglycerides (mmol l−1) | 1.91 | 1.69 | −0.39 |
| Glucose (mmol l−1) | 5.72 | 5.27 | −0.5 |
| Insulin (uU ml−1) | 21 | 14 | −5.0 |
| IL-6 (pg ml−1) | 4.5 | 3.1 | −1.5 |
| CRP (mg l−1) | 3.3 | 1.9 | −1.4 |
| Systolic BP (mmHg) | 127 | 124 | −2 |
| Diastolic BP (mmHg) | 86 | 82 | −4 |
| Physical activity level (min week−1) | 48 | 195 | +114 |
| Total daily calorie intake (calories day−1) | 2340 | 1950 | −340 |
| Fiber intake (g) | 15 | 25 | +9 |
| Saturated fat (% calories) | 14 | 9 | −5 |
| Ratio of omega-6∶3 | 12 | 6 | −5 |
Abbreviations: BMI, body mass index; BP, blood pressure; CRP, C-reactive protein; HDL, high-density lipoprotein; WHR, waist-to-hip ratio.
a
Data are derived from Esposito et al.74