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. 2012 Apr 23;14(3):465–475. doi: 10.1038/aja.2012.20

Table 2. Molecular markers of normal adult stem cells in various organs, and their expression in the epididymis without evidence that they are stem cell markers.

  Braina Liver Intestine Kidney Prostate Epididymal transcriptb Epididymal proteinc
  Mouse/human Human Mouse/human Human Mouse/human Human Mouse/bull/human
Abcg2 +         + (Ref. 20) Mouse caput epithelial microvilli, caput and corpus interstitial endothelial cells165
Ascl 2     +     + (Ref. 20)  
Bmi-1 +   +        
CD9 +         + (Ref. 20) Bull corpus and cauda epithelium166
CD24       +   + (Refs. 20 and 38)  
CD29   +         Human cultured cells8
CD44         + + (Refs. 20 and 38) Human cultured cells; mouse basal cells8
CD49b         +    
CD49f   +          
CD73   +          
CD81 +         + (Refs. 20 and 38)  
CD90   +          
CD95 +            
CD117         +    
CD133 + +   + +   Human cultured cells (j); mouse principal cells microvilli except initial segment167
CD144 +            
CD146 + +          
CD184 +            
CK6a         +    
DCAMKL-1     +     + (Ref. 20)  
EpCAM   +          
Lgr5     +     + (Ref.20)  
Musashi-1     +        
mTERT     +        
Nestin +         + (Ref. 38)  
OLFM4     +     + (Ref. 20)  
PTEN     +     + (Ref. 20) Mouse caput epithelium apical surface, especially initial segment stereocilia21
Sca-1         +    
sFRP5     +     + (Ref. 20)  
SOX4     +     + (Ref. 20)  
SOX9     +     + (Ref. 20)  
WIP1     +        
Reference 6 161 162 12 Murine,163, 164 20, 38 8, 21, 165–167
          human13    
a

In neural stem cells not exclusive to adults.

b

Expression reported in human epididymal transcriptome.20, 168 No listed markers are found in the proteome.39

c

Protein localized by immunohistology in epididymal cells.