Table 3.
Top 10 differentially expressed genes between the high and low pain groups based on p-values
| Gene Symbol | Genes title | Function | p-value | Fold-Change | Expression in high pain group |
|---|---|---|---|---|---|
| BATF2 | basic leucine zipper transcription factor, ATF-like 2 | Protein binding/protein dimerization activity | 0.0002 | 2.064 | up |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | Cysteine-type endopeptidase activity | 0.0003 | 2.732 | up |
| CCR1 | chemokine (C-C motif) receptor 1 | C-C chemokine binding/ C-C chemokine receptor activity | 0.0004 | 2.220 | up |
| CD69 | CD69 molecule | transmembraine signaling receptor activity | 0.0008 | 4.217 | up |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | molecular function/protein binding | 0.0010 | 2.493 | up |
| LY6E | lymphocyte antigen 6 complex, locus E | adrenal gland development/ epinephrine secrertion/norepinephrine metabolic process | 0.0100 | −2.102 | down |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | NAD+ADP-ribosyltransferase activity | 0.0112 | −2.048 | down |
| RPL23 | ribosomal protein L23 | Structoral constituent of ribosome | 0.0191 | −2.166 | down |
| RPL7 | ribosomal protein L7 | DNA, RNA, mRNA binding/ protein homodimerization activity | 0.0237 | −2.869 | down |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | Copper ion binding | 0.0312 | −2.243 | down |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | protein binding/ serine-type endopeptidase inhibitor activity | 0.0316 | −2.074 | down |
| SH2D1B | SH2 domain containing 1B | protien binding, bridging | 0.0360 | −2.767 | down |