Table 4.
Top 10 differentially expressed genes between the high and low catastrophizing groups based on p-values
| Gene Symbol | Genes title | Function | p-value | Fold-Change | Expression in high catastrophizing |
|---|---|---|---|---|---|
| TNS1 | Tensin 1 | Actin binding/protein binding | 0.026 | 4.005 | up |
| LTF | Lactotransferrin | Ferric iron binding/serune-type endopeptidase activity/DNA binding | 0.029 | 3.345 | up |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | Creatine transmembrane transporter activity/creatine:sodium symporter activity | 0.014 | 3.064 | up |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | function is yet unknown | 0.023 | 2.647 | up |
| SPP1 | secreted phosphoprotein 1 | Cytokine activity/extracellular metrix binding | 0.046 | 2.363 | up |
| PF4V1 | Platelet factor 4 variant 1 | Chemokine activity/ heparin binding | 0.008 | −5.639 | down |
| CLEC4D | C-type lectin domain family 4, member D | Carbohydrate binding | 0.001 | −3.151 | down |
| 10SEP | septin 10 | GTP binding | 0.003 | −2.353 | down |
| FAS | Fas (TNF receptor superfamily, member 6) | Identical protein binding/ signal transducer activity | 0.005 | −2.214 | down |
| USP46 | ubiquitin specific peptidase 46 | Ubiquitin-specific protease activity | 0.006 | −2.211 | down |