Table 5.
Prognostic factors in univariate and multivariate Cox proportional-hazards regression models for disease-specific survival in patients with stage II and III disease
| |
|
Univariate (Log-rank) |
|
Multivariate |
||
|---|---|---|---|---|---|---|
| n | 5-yr DSS(%) | p | HR | 95%CI | p | |
| Age |
|
|
|
|
|
|
| <70 |
65 |
54 |
|
|
|
|
| ≥70 |
33 |
64 |
0.63 |
|
|
|
| Gender |
|
|
|
|
|
|
| female |
22 |
64 |
|
|
|
|
| male |
76 |
56 |
0.49 |
|
|
|
| Main location |
|
|
|
|
|
|
| middle or lower |
78 |
61 |
|
|
|
|
| upper |
20 |
44 |
0.24 |
|
|
|
| WHO pathological type |
|
|
|
|
|
|
| differentiated |
39 |
69 |
|
1 |
|
|
| undifferentiated |
59 |
50 |
0.077 |
1.7 |
0.86-3.3 |
0.13 |
| Depth of invasion |
|
|
|
|
|
|
| T1-3 |
48 |
85 |
|
1 |
|
|
| T4 |
50 |
32 |
<0.001 |
5.5 |
2.5-12 |
<0.001 |
| Lymph node metastasis |
|
|
|
|
|
|
| negative |
20 |
89 |
|
1 |
|
|
| positive |
78 |
49 |
0.004 |
3.0 |
0.92-9.9 |
0.070 |
| EphA2 |
|
|
|
|
|
|
| low |
18 |
83 |
|
1 |
|
|
| high |
80 |
52 |
0.019 |
1.7 |
0.52-5.7 |
0.38 |
| EphA4 |
|
|
|
|
|
|
| low |
28 |
79 |
|
1 |
|
|
| high |
70 |
49 |
0.007 |
2.6 |
1.1-6.3 |
0.039 |
| ephrinA1 |
|
|
|
|
|
|
| low |
40 |
51 |
|
|
|
|
| high | 58 | 62 | 0.39 | |||