Table 3. Incidence of disease, bone loss and extent of Aa colonization in ltxA mutant and control rats.
Diseased | Bone Loss | Aa counts/total counts ×10-4 | ||
2 wks | 12 wks | |||
Control | ||||
1–1 | no | 72.87 | 0.000 | 0.000 |
1–2 | no | 97.05 | 0.000 | 0.000 |
1–3 | no | 105.65 | 0.000 | 0.000 |
1–4 | no | 125.40 | 0.000 | 0.000 |
1–5 | no | 90.93 | 0.000 | 0.000 |
avr±SD | 98.377±19 | 0.000 | 0.000 | |
ltxA mutant | ||||
2–2 | no | 100.86 | 0.000 | 0.000 |
2–3 | no | 109.79 | 80.300 | 0.310 |
2–4 | no | 105.01 | 3.300 | 0.230 |
2–5 | no | 98.57 | 0.580 | 0.000 |
2–6 | no | 105.70 | 11.190 | 1.920 |
2–7 | yes | 118.59 | 2.500 | 0.490 |
avr±SD | 106.416±7.1 | 16.31±31.6 | 0.49±0.72 | |
DF2200 (wt) | ||||
3–1 | yes | 116.72 | 0.160 | 0.230 |
3–2 | yes | 128.20 | 199.000 | 0.200 |
3–3 | yes | 115.26 | 0.000 | 0.000 |
3–4 | no | 117.61 | 0.000 | 0.000 |
3–5 | yes | 130.07 | 1.100 | 0.000 |
3–6 | no | 106.24 | 1.390 | 1.770 |
avr±SD | † | 119.014±8.1 * | 33.61±81.0 | 0.36±0.69 |
WT compared to Control or ltxA mutant is significantly different p<0.05 by ANOVA and Tukey's Studentized Range post-hoc test.
WT is significantly different from Control or ltxA mutant by Fisher's Exact Test and Cochran Armitage Trend test.