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. 2013 Jul 4;13:157. doi: 10.1186/1472-6882-13-157

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Copyright © 2013 Ling-Sing Seow et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of aqueous extracts on the neuritogenic activity of PC-12 cells. The percentage of neurite-bearing cells of PC-12 cells treated with various concentrations of aqueous extracts ranged from 25 to 100 μg/ml. Cells in complete F-12 K medium without treatment served as a negative control. Cells treated with 50 ng/ml of NGF or 50 μg/ml of H. erinaceus (HE) served as positive controls. Data were expressed as means ± standard deviation (n = 3). Means with different alphabets shows significant difference p < 0.05. *** p < 0.001 compared to NGF.