Fig. 3.

Replication of SeV Cm^* in wild-type cells and in STAT1 deficient cells. Parental SeV Wt (wild type) and SeV Cm^* were inoculated to the parental STAT1^+/+2fTGH cells (left) and to its STAT1 deficient (STAT1^−/−) derivative, U3A cells (right) at an m.o.i. of 5. Cells were collected at the hours indicated. The cell lysates were immunoblotted with a mixture of anti STAT1 and anti STAT2 antibodies (top). Titers of SeV Wt (open circle) and SeV Cm^* (closed circle) in the culture fluid are shown (bottom) (Modified from Ref. 26).