Table 3.
Prevalence of pfdhfr and pfdhps alleles in Sudan before and after adoption of ACT
| pfdhfr/pfdhps allele | 2003 % | 2012 % | p-value [[20],[52]] |
|---|---|---|---|
|
51I/108N |
90[20] 84[52] |
100 |
0.004/0.001 |
|
59R |
1[20] 0[52] |
1.7 |
0.477/1.000 |
|
436A |
0[52] |
7.8 |
0.069 |
|
437G |
89[20] 0[52] |
77.3 |
0.013/0.000 |
|
516F |
|
1.7* |
|
|
K540 |
20[52] |
21.5 |
0.000 |
|
540E |
79[20] |
76.9 |
0.860 |
|
540K/E |
80[52] |
1.5 |
0.000 |
|
581G |
14[20] 10[52] |
33.8 |
0.001/0.007 |
|
581A/G |
10[52] |
1.5 |
0.202 |
| A613 | 100[20,52] | 100 | 1.000 |