Table 3. Hazard ratios (HRs) and 95% confidence intervals (CI) for the adjusted associations between elevated baseline high-sensitivity C-reactive protein (hsCRP>3.0 mg/L) and first sepsis episodes.

Model	N	Events	Hazard Ratio (95% CI)
Crude (unadjusted) HR	29,667	972	1.68 (1.48–1.90)
Adjusted for age, sex, race, region	29,667	972	1.86 (1.64–2.12)
Additional adjustment for education and income	29,644	970	1.77 (1.56–2.01)
Additional adjustment for smoking and alcohol use	28,959	940	1.70 (1.50–1.94)
Additional adjustment for chronic medical conditions* and statin use	26,999	881	1.56 (1.36–1.79)

Total of 30,183 REGARDS participants included in the analysis.

^*Coronary artery disease, diabetes, dyslipidemia, hypertension, chronic kidney disease, chronic lung disease.