Figure 1. EGFR-TKI inhibits cell proliferation.

HSC-3 (A) and A549 (B) cells were treated with different concentrations (1-100 μM) of AG1478 for different durations (24-96 hrs). Then, cell proliferation was measured (n = 6), using a kit and absorbance at 530 nm or 630 nm. Bars represent average ± standard deviation (SD) of three independent experiments. *P < 0.001 by student's t test (vs DMSO-treated cells).