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. 2013 Mar 31;4(4):550–559. doi: 10.18632/oncotarget.939

Figure 3. EGFR-TKI increases phosphorylation of STAT3.

(A) HSC-3 cells treated with EGF and/or AG1478 for up to 24 hrs were analyzed on western blotting, using antibodies to pEGFR (175 kDa), EGFR (175 kDa), pSTAT3 (86 kDa), and STAT3 (86 kDa). (B) HSC-3 cells treated with AG1478 or ZD1478 for 10 min or 24 hrs were analyzed on western blotting, using antibodies to pEGFR (175 kDa), EGFR (175 kDa), pSTAT3 (86 kDa), and STAT3 (86 kDa). D, DMSO.

Figure 3