Table 4. Change in treatment intensity from initial perceived clinical risk compared against GC risk.

Timepoint	Perceived Risk	GC Risk	Decrease	No Change	Increase
Adjuvant	high	low	20 (50%)	18 (45%)	2 (5%)
		high	3 (5%)	35 (58.3%)	22 (36.7%)
	low	low	15 (18.8%)	60 (75%)	5 (6.3%)
		high	3 (5%)	24 (40%)	33 (55%)
Salvage	high	low	48 (45.7%)	53 (50.5%)	4 (3.8%)
		high	1 (3.3%)	17 (56.7%)	12 (40%)
	low	high	4 (8.9%)	15 (33.3%)	26 (57.8%)

Low (High) Perceived Risk = < half (> half) of clinicians initially recommend treatment

Low (High) GC Risk at Advjuvant timepoint = 5 year predicted probability < 6% (> 6%)

Low (High) GC Risk at Salvage timepoint = 3 year predicted probability < 18% (> 18%)