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. 2013 Jul 23;8(7):e69477. doi: 10.1371/journal.pone.0069477

Figure 2. Transendothelial neutrophil migration is inhibited by anti- UNC5B antibody.

Figure 2

A) PMN transmigration studies were performed in transwells using fMLP as chemoattractant in the lower compartment. PMNs were pre-incubated with either anti-UNC5B antibody or IgG control prior to transmigration. Number of transmigrated PMNs was assessed by MPO measurement. B) Passive flux of FITC Dextran across HMEC endothelium monolayers. Flux was detected by measurement of passed FITC Dextran in the basal compartment (n = 6 per condition; *P<0.05 as indicated).